期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

RUNX3基因的抑癌机制及其与肿瘤关系研究进展 被引量：2

下载PDF
导出
作者 秦娜 张勇
机构地区 广西医科大学第一附属医院放疗科
出处 《广西医学》 CAS 2007年第6期848-850,共3页 Guangxi Medical Journal
基金 广西自然科学基金资助课题(桂科基0663029)
关键词 RUNX3基因 肿瘤 抑癌机制
分类号 R730.231 [医药卫生—肿瘤]
  • 相关文献

参考文献28

  • 1Bangsow C,Rubins N,Glusman G,et al.The RUNX3 gene-sequence,structure and regulated expression[J].Gene 2001,279(2):221-232.
  • 2Kato N,Tamura G,Fukase M,et al.Hypermethylation of the RUNX3 gene promoter in testicular yolk sac tumor of infants[J].Am J Pathol,2003,163(2):387-391.
  • 3Coffman JA.Runx transcription factors and the developmental balance between cell proliferation and differentiation[J].Cell Biol Int 2003,27(4):315-324.
  • 4Tang YY,Shi J,Zhang L,et al.Energetic and functional contribution of residues in the core binding factor beta(CBFbeta) subunit to heterodimerization with CBFalpha[J].J Biol Chem 2000,275(50):39 579-39 588.
  • 5Yang N,Zhang L,Zhang Y,et al.An important role for RUNX3 in human L1 transcription and retrotransposition[J].Nucleic Acids Res 2003,31(16):4 929-4 940.
  • 6Ito Y.Molecular basis of tissue-specific gene expression mediated by the runt domain transcription factor PEBP2/CBF[J].Genes Cells 1999,4(12):685-696.
  • 7Lund AH,van Lohuizen M.RUNX:a trilogy of cancer genes[J].Cancer Cell 2002,1(3):213-215.
  • 8Hug BA,Ahmed N,Robbins JA,et al.A chromatin immunoprecipitation screen reveals protein kinase Cbeta as a direct RUNX1 target gene[J].J Biol Chem,2004,279(2):825-830.
  • 9Ito Y,Miyazono K.RUNX transcription factors as key targets of TGF-beta superfamily signaling[J].Curr Opin Genet Dev,2003,13(1):43-47.
  • 10Zhang YW,Yasui N,Ito K,et al.A RUNX2/PEBP2 alpha A/CBFA1 mutation displaying impaired transactivation and Smad interaction in cleidocranial dysplasia[J].Proc Natl Acad Sci USA,2000,97(19):10 549-10 554.

二级参考文献14

  • 1李锦毅,郑华川,杨琳,徐蕾,杨雪飞,高红,张荫昌,辛彦.胃癌中PTEN异常表达与围基因微卫星的杂合性缺失[J].中华肿瘤杂志,2004,26(7):389-392. 被引量：32
  • 2Laurent Puig P, Legoix P, Bluteau O, et al. Genetic alterations associated with hepatocellular carcinomas define distinct pathways of hepoatocarcinogenesis. Gastroenterology, 2001, 120: 1763-1773.
  • 3Bergsland EK. Molecular mechanisms underlying the development of hepatocellular carcinoma. Semin Oncol, 2001, 28: 521-531.
  • 4Li QL, Ito K, Sakaura C, et al. Causal relationship between the loss of RUNX3 expression and gastric cancer. Cell, 2002, 109:113-124.
  • 5Fang W, Piao Z, Simon D, et al. Mapping of a minimal deleted region in human hepatocellular carcinoma to l p36.13-p36.33 and mutational analysis of the RIZ (PRDM2) gene localized to the region.Genes Chromosomes Cancer, 2000, 28: 269-275.
  • 6Zaidi SK, Sullivon AJ, Wijnen AJV, et al. Integration of Runx and Smad regulatory signals at transcriptionally active subnuclear sites.Proc Natl Acad Sci, 2002, 99: 8048-8053.
  • 7Song BC, Chung YH, Kim JA, et al. Transforming growth factorbetal as a useful serologic marker of small hepatocellular carcinoma.Cancer, 2002, 94: 175-180.
  • 8Matuzaki K, Date M, Furukawa F, et al. Regulatory mechanisms for transforming growth factor beta as an autocrine inhibitor in human hepatocellalar carcinoma: implications for roles of smads in its growth.Hepatology, 2000, 32: 218-227.
  • 9Kato N, Tamura G, Fukase M, et al. Hypermethylation of the runx3 gene promoter in testicular yolk sac tumor of infants. Am J Pathol,2003,163:387-391.
  • 10Li QL, Ito K, Sakakura C, et al. Causal relationship between the loss of runx3 expression and gastric cancer. Cell, 2002,109:113-124.

共引文献30

同被引文献18

  • 1武立鹏,朱卫国.DNA甲基化的生物学应用及检测方法进展[J].中华检验医学杂志,2004,27(7):468-474. 被引量：25
  • 2Li QL,Kim HR,Kim WJ,et al.Transcriptional silencing of the RUNX3 gene by CpG hypermethylation is association with lung cancer[J].Biochem Biophys Res Commun,2004,314(1):223-228.
  • 3Costello JF,Furhwald MC,Smiraglia DJ,et al.Aberrant CpG-island methylation has non-random and tumor-type-specific patterns[J].Nat Genet,2000,24(2):132-138.
  • 4Palmisano WA,Divine KK,Saccomanno G,et al.Predicting lung cancer by detecting aberrant promoter methylation in sputum[J].Cancer Res,2000,60(21):5 954-5 958.
  • 5Verma M,Maruvada P,Srivastava S.Epigenetics and cancer[J].Crit Rev clin Lab Sci,2004,41(5-6):585-607.
  • 6Lo KW,Huang DP.Genetic and epigenetic changes in nasopharyngeal carcinoma[J].Semin Cancer Biol,2002,12(6):451-462.
  • 7Chang HW,Chan A,Kwong DL,et al.Evaluation of hypermethylated tumor suppressor genes as tumor markers in mouth and throat rinsing fluid,nasopharyngeal swab and peripheral blood of nasopharygeal carcinoma patient[J].Int J Cancer,2003,105(6):851-855.
  • 8Tan SH,Ida H,Goh BC,et al.Analyses of promoter hypermethylation for RUNX3 and other tumor suppressor genes in nasopharyneal carcinoma[J].Anticancer Research,2006,26(6B):4 287-4 292.
  • 9Shao JY,Wang HY,Huang XM,et al.Genome-wide allelotype analysis of sporadic primary nasopharyngeal carcinoma from southern China[J].Int J Oncol,2000,17(6):1 267-1 275.
  • 10杨国华,刘海鹰.Galectin-3与肿瘤的研究进展[J].中华肿瘤防治杂志,2007,14(22):1755-1758. 被引量：18

引证文献2

二级引证文献3

广西医学
2007年 第6期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部