肺支原体研究进展

Advance in Research on Mycoplasma pulmonis

肺支原体是实验大鼠和小鼠的重要致病微生物,所导致的鼠呼吸系统支原体病也是研究人类呼吸系统感染的动物模型。肺支原体膜蛋白及其变异、致病机理和毒力的影响因素等一直是肺支原体研究的焦点问题,本文从分子水平对其进行了较为详细的介绍,并简要综述了检测方法的研究进展。

M. pulmonis is not only an important pathogenic organism to laboratory rats and mice, but also is an extremely suitable model organism to study pathogenesis of human respiratory system. Much research about M. pulmonis is focused on the membrane protein, the variation of the membrane protein, pathogenicity, virulence factors, and so on. This paper gives a detailed introduction in molecular level, and summarises the advance of diagnostic methods.