免疫栓塞治疗在中晚期肾癌中的应用

Application of immunotherapy-embolization in treatment of middle-stage and advanced renal cell carcinoma

目的评价免疫栓塞治疗对中晚期肾癌的疗效。方法46例中晚期肾癌患者随机分为A、B两组,A组24例采用化疗栓塞,B组22例采用免疫栓塞。结果B组无论是T细胞活性,还是近期疗效、Karnofsky评分均好于A组,差异具有显著性(P<0.05)。结论免疫栓塞不仅提高了治疗的有效率,而且改善了患者的生活质量。对中晚期肾癌患者,免疫栓塞治疗是一种较好的方法。

Objective To evaluate the efficacy of immunotherapy-embolization of renal artery in treatment of middle-stage and advanced renal cell carcinoma. Methods Forty-six cases of middle-stage and advanced renal cell carcinoma were randomized into two groups. Group A （24 cases） was treated with chemotherapy and embolization of renal artery. Group B （22 cases） was treated with immunotherapy-embolization of renal artery. Results There were significant differences between these two groups in T-cell activation, short- term therapeutic efficacy and Karnofsky score（P 〈 0.05）. Conclusion Immunotherapy-embolization not only enhances the effectiveness of treatment, but also improve the quality of life. It is an effective treatment for renal carcinoma.