经尿道电切联合丝裂霉素治疗腺性膀胱炎

Transurethral resection combining with Mitomycin C instillation for the treatment of cystitis glandularis

目的：探讨腺性膀胱炎治疗的有效方法.方法：对55例腺性膀胱炎患者以经尿道前列腺电切镜电切除病变组织,3例开放手术电灼膀胱病变部位并同时去除合并的相关诱因,术后3～7天均用丝裂霉素30 mg膀胱灌注,每周1次,连续8次;5例单纯丝裂霉素膀胱灌注8次.结果：随访6～36个月,63例患者中55例电切术后配合丝裂霉素灌注痊愈52例,好转2例;3例开放手术痊愈2例,好转1例;5例单纯丝裂霉素膀胱灌注痊愈3例,好转1例,其他转归2例.结论：经尿道电切或电灼病变组织,需去除导致腺性膀胱炎的相关诱因,术后大剂量丝裂霉素膀胱灌注,可缓解或治愈腺性膀胱炎.

Objective：To evaluate the comprehensive treatment outcomes of cystitis glandularis. Methods：Totally 63 Cases of cystitis glandularis were included in this study. Transurethral resection was performed followed by Mitomycin C bladder istillation once a week for 8 weeks in 55 cases,open surger with Mitomycin C instillation in 3 cases and Mitomycin C instillation alone in 5 cases. Results：The mean follow-up was 28 months （range 6 to 36 months）. Of the 63 cases, 57 fully recovered and 4 improved. Conclusions：Transurethral resection or galvanocautery with the bladder instillation with Mitomycin C is the essential therapy for cystitis glandularis.