代谢综合征与脂肪肝的相关性探讨

The exploration of correlation between metabolic syndrome and fatty liver

目的:探讨代谢综合征(MS)与脂肪肝的相关性。方法:对参加健康体检的564名处、厅级干部,进行身高、体重、腰围、血压、血脂、血糖、血尿酸等指标检测,空腹行腹部B超检查,并进行统计分析。结果:1564例受检者中,MS和脂肪肝检出率分别为23.05%和20.39%,MS组脂肪肝的检出率明显高于非MS组,是非MS组的5倍。2脂肪肝组中MS、中心肥胖、高血压、血脂异常、糖代谢异常的检出率明显高于非脂肪肝组(P<0.01),脂肪肝合并代谢综合征的发生率是非脂肪肝组的4.4倍。3logistic回归分析显示,MS与脂肪肝、BMI、TG、HDL-C、UA、腰围、高血压呈显著相关,提示脂肪肝、肥胖或中心肥胖、脂代谢紊乱、高尿酸血症、高血压是MS的危险因素。结论:MS与脂肪肝密切相关,脂肪肝患者具有MS各组分集聚的特征,MS的患病率明显升高,脂肪肝是MS的一个重要的危险因素。

Objective ：To explore the relationship between metabolic syndrome （MS） and fatty liver. Methods ： 564 cases of cadres taking part in the healthy examination received measurement of the body heights, weights and waist circumference（WC） ,blood pressure, the level of blood lipids, glucose, serum urate concentration. Type B ultrasonic waves of liver was also tested. MS was diagnosed according to IDF （2005.4）. Results ：①The prevalences of metabolic syndrome and fatty liver were 23.05% and 20.39% respectively. The prevalence of fatty liver in MS group were significantly higher than that of non-MS group. It was 5 times higher than that of non-MS group. ②The prevalence of MS; central obesity, hypertension, dyslipidemia, glucose metabolic abnormality in fatty liver group were significantly higher than that of non-fatty liver group （P〈0.01） . The prevalence of fatty liver merged with MS was 4.4 times higher than that of non-fatty liver group. ③Logistic regression analysis showed that there was significant correlation between fatty liver, BMI, TG, HDL-C, UA, WC, hypertension and MS. It indicated that fatty liver, obesity or central obesity, lipid metabolism disorder, hyperuricemia, hypertension were the risk factor for MS. Conclusion：There is a close relation between MS and fatty liver. The patients with fatty liver has the characteristic of MS various components gathering together. The morbidity of MS in the patients suffered by fatty liver goes up obviously. Fatty liver is the most important risk factor of MS.