摘要
利用分子模型化软件（InsightⅡ）研究了两类钾高子通道开放剂（KCO）的构象，构象分析的结果说明这两类KCO具有共同的药效团结构，这有助于进一步设计新的KCO分子。
The conformation analysis of two kinds of K+ Channel Openner (KCO)is investigated by using molecular modeling software (Insight Ⅱ). The results of the conformution analysis show that the two kinds of KCO have a common hydrogen bond donnor region, a counon aromatic ring region and an aliphatic region. These are helpful to further designing new KCO compounds.
出处
《计算机与应用化学》
CAS
CSCD
1997年第1期31-33,共3页
Computers and Applied Chemistry
基金
国家自然科学基金
