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正常T细胞表达和分泌的活性调节蛋白与糖尿病视网膜病变 被引量:1

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摘要 正常T细胞表达和分泌的活性调节蛋白(RANTES)与特异性受体结合,通过对炎症效应细胞的强烈趋化作用以及诱导活化T细胞、调节Th1/Th2平衡和提高抗原特异性抗体应答,引起炎症反应。糖尿病视网膜病变(DR)的发病与很多炎症因素有关,DR患者血清中RANTES的表达上调,视网膜内层RANTES阳性着染,均提示RANTES可能参与DR的发病。这一过程受多种因素的调控,共同促进了DR的发生发展。
出处 《中华眼底病杂志》 CAS CSCD 北大核心 2007年第4期301-303,共3页 Chinese Journal of Ocular Fundus Diseases
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