老年高血压病患者餐后代谢状态与颈动脉超声检测和分析

Detection and analysis of postprandial metabolism and carotid artery ultrasound in elderly hypertensive patients

目的:采用彩色多谱勒超声通过颈动脉视窗就老年高血压病患者日常餐后代谢状态与动脉粥样硬化之间的关系进行研究。方法:选择空腹血糖(FBG)<6.1mmol/L且空腹甘油三酯(TG)<1.8mmol/L的老年高血压病患者为研究对象,根据所测结果将餐后2h血糖(2hPPG)≥7.8mmol/L作为切点分为A、B两组,分别对两组患者血糖、血脂、颈动脉内膜中层厚度(IMT)、粥样斑块等指标进行比较研究。结果:A、B两组餐前血糖、血脂水平无明显差别,而餐后2h血糖及TG水平B组明显高于A组(P<0.001)。结论:血糖正常的老年高血压病患者中,在进食日常餐后约有58%(33/57)的患者出现餐后高血糖、高血脂,其IMT及斑块的发生率明显高于餐后糖脂代谢正常者,反映了日常餐后代谢异常与全身动脉粥样硬化密切相关。

Objective： To study the relationship of the postprandial metablism after daily meal and atherosclerosis with the use of color Doppler ultrasound examination of carotid windows. Methods： The elderly hypertenfive patients whose fasting blood glucose （FBG） 〈 6. 1mmol/L and fasting triglyceride 〈 8. 1mmol/L were studied. Color Doppler ultrasonography of carotid ateries were used to examine all subjects group A and B were divided according to the cut-off point of 2-hour postprandial blood glucose ≥7.8mmol/L. Blood glucose, cholesterol, carotid atery intima-media thickness（IMT）, atheromatous plaque and other indicators were compared. Results： There was no significant difference of fasting blood glucose between group A and B. But 2-hour postprandial blood glucose and triglyceride levers were tfignifeantly higher in group B （ P 〈0.05）. And carotid artery IMT ＆ atheromtous plague were hnproved as well.Conclusion：Postprandial hyperglycemia,hyperlipidemia occurs on about 58% （33/57 vs） eldly hypertensive patients with normal fasting blood glucose. The IMT and plaque rate in the postprandial metabolism are significandy higher than normal. The relationship of daily postprandial metabolism and ateroclerosis was closely related in elderly hypertensive patients.