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B细胞激活因子与系统性红斑狼疮

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摘要 B细胞激活因子(B cell activating factor belonging to the TNF family, BAFF), 又称 TAIL-1 (TNF-and apoptosis ligand- related leukocyte-expressed ligand 1),BLyS (B lymphocyte stimulator) ,THANK(TNF homology that activates apoptosis, nuclear factor-κB and c-Jun NH2-terminal kinase),zTNF4或TNFSF-13b,是TNF家族新成员,1999年由Mukhopadhyay等克隆而成。
出处 《中华风湿病学杂志》 CAS CSCD 2007年第7期439-441,共3页 Chinese Journal of Rheumatology
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参考文献22

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  • 2Zhang J, Roschke V, Baker KP, et al. Cutting edge: a role for B lymphocyte stimulator in systemic lupus erythematosus. J Immunol, 2001, 166: 6-10.
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  • 6Hase H, Kanno Y, Kojima M, et al. BAFF/BLyS can potentiate B-cell selection with the B-cell coreceptor complex. Blood, 2004, 103: 2257-2265.
  • 7Gavin AL, Duong B, Skog P, et al. Delta BAFF, an alternate splice isoform that regulates receptor binding and biopresentation of the B cell survival cytokine, BAFF. J Biol Chem, 2003, 278: 38220-38228.
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