摘要
目的探讨高血压病中D－Ⅱ聚体（DD）的临床意义。方法用ELISA法测定高血压病Ⅱ－Ⅲ期159例患者的DD。结果高血压病Ⅱ期不同性别中DD含量比较及高血压Ⅱ期与正常对照组DD含量比较均无差异（P＞0．05）。急性脑梗塞、多发性脑梗塞后与正常对照组DD含量比较有显著差异（P＜0．01）。急性脑梗塞组与陈旧性脑梗塞DD含量比较有显著差异（P＜0．01）。急性脑出血、陈旧性脑出血与正常对照组DD含量比较有显著差异（P＜0．01），而急性脑出血与陈旧性脑出血DD含量比较无差异（P＞0．05）。腔隙性脑梗塞与正常对照组DD含量比较无差异（P＞0．05）。结论测定高血压患者DD有助于血栓性疾病的早期诊断，对判断疗效，预后的估计有一定意义。
D-dimer in hypertensive patient and its clinical significance were investigated. D-dimer wasmeasured by ELISA in 159 Patients with hypertension. Result showed that D-dimer haven't discrepancy forcomparison of different sex group of stage Ⅱ or in patients of stage Ⅱ lacunar infarction be compared withnormal group (P>0. 05). D-dimer in acute cerebral infarct and multiplicity cerebral infarct is higher than thatin normal group (P<0.01) D-dimer in acute cerebral infarct is higher than that in old cerebral infarct (P<0.01 ). D-dimer is significantly higher in the patients in acute cerebral hemorrhage and old cerebral hemorrhage compared with nomal controls (P<0. 01). While no change has been found in ACH compared withOCH (P>0.05). D-dimer may help to diagnose of thrombolism diseases early. It has value to predict the effect and prognosis of cases.
关键词
高血压
D-Ⅱ聚体
临床研究
Hypertension Cerebral infarct Cerebral hemorrhage
