沙苑子补充对疲劳训练大鼠力竭运动后机能状态及有氧运动能力的影响

Effects of Astragalus Complanatus Supplement on Function and Aerobic Sport Ability of Rat after Exhaustive Exercise

目的:观察沙苑子补充对力竭运动后大鼠运动后机能状态及有氧运动能力的影响。方法:10周龄雄性SD大鼠40只,随机分为安静对照组(C)、沙苑子补充组(A)、运动组(E)和沙苑子运动组(AE),每组10只;A组和AE组分别灌服沙苑子生理盐水溶液(50 mg.kg-1.d-1),C组和E组灌服同体积生理盐水。补充期间各组大鼠先进行2周适应性游泳训练,然后E组与AE组进行4周递增负荷游泳训练并于第4周末进行力竭运动实验。结果:1)AE组大鼠游泳至力竭的时间显著高于E组2;)力竭运动后E组及AE组大鼠血清乳酸浓度均显著高于C组,AE组血清乳酸浓度显著高于E组;3)力竭运动后E组及AE组大鼠骨骼肌MDA浓度均显著高于C组,但AE组大鼠骨骼肌MDA浓度显著低于E组;4)力竭运动后E组及AE组大鼠血清睾酮含量均较C组显著降低,血清皮质酮含量均较C组显著提高,T/C比值较C组显著降低。AE组血清睾酮含量显著高于E组,血清皮质酮含量显著低于E组,T/C比值显著高于E组。力竭运动后AE组大鼠血清LH含量显著高于C组和E组。结论:长期补充沙苑子可以改善疲劳训练大鼠力竭运动后的机能状态,提高有氧运动能力。

Objective： To observe effects of astragalus complanatus supplement on function and aerobic sport ability after exhaustive exercise and aerobic capacity in Rat. Methods： Forty 10-week old male SD rat were randomly divided into four groups （n=10）. Group A and AE rats were effused astragalus complanatus （50mg·kg^-1·d^-1） orally, whereas group C and E rats were effused saline solution in same volume respectively. After all rats finished 2 weeks of adap- tation swimming training, the E and AE rats were taken 4 weeks of increment load swimming training. In the last day of the 4th week, the E and AE rats were forced to take a swimming exercise until exhaustive. Results： 1） The AE rats swam significantly longer than E rats in exhaustive exercise. 2） After the exhaustive swimming, the serum lactate content in E and AE rats were significantly higher than C rats, whereas the serum lactate content in AE rats were significantly higher than E rats. 3） After the exhaustive swimming, the skeletal muscle MDA content in E and AE rats were significantly higher than C rats, whereas the muscle MDA content in AE rats were significantly lower than E rats. 4） After the exhaustive swimming, the serum testosterone content, testosterone/corticosterone ratio in E and AE rats were significantly lower than C rats, whereas the serum corticosterone content were significantly higher than C rats. The serum T content and testosterone/corticosterone ratio in AE rats were significantly higher than E rats, whereas the serum, corticosterone content were significantly lower than C rats. After the exhaustive swimming, the serum LH content in AE rats was significantly higher than C and E rats. Conclusion： Astragalus complanatus supplement can improve strength and conditioning after exhaustive exercise, and enhance aerobic capacity in rat.