1Bordone L, Guarente L Calorie restriction, SIRT1 and metabolism, understanding longevity. Nat Rev Mol Cell Biol, 2005; 6 (4): 298-305
2Guarente L, Picard F. Calorie restriction - the SIR2 connection. Cell, 2005; 120 (4): 473-482
3Ingram DK, Anson RM, de Cabo R et al. Development of calorie restriction mimetics as a prolongevity strategy. Ann N Y Acad Sci, 2004; 1019:412 -423
4Masaro EJ. Nutrition as a modulator of tile aging proceas. Physiologist, 1984; 27 (2): 98-101
5Koubova J. Guarente L. How does calorie restriction work? Genes Dev, 2003; 17 (3) : 313 -321
6Walford RL, Mock D, Verdery R et al. Calorie restriction in biosphere 2: alterations in physiologic, hematologic,hormonal, and biochemical parameters in humans restricted for a 2 -year period.J Gerontol A Biol Sci Med Sci, 213112; 57 (6): 8211-224
7Beckman KB, Ames BN. The free radical theory of aging matures. Physiol Rev, 1998; 78 (2): 547-581
8Vaziri H, Dessain SK, Eaton Ng et al. hSIR2 ( SIRT 1 ) thnctions as an NAD - dependent p53 deacetylase. Cell, 2001; 107 (2): 149-159
9Luo J, Nikolaev AY, Imai Set al. Negative control of p.53 by Sir2alpha promotes cell survival under stress. Cell, 2001; 107 (2): 137-148
10Langley E, Pearson M, Faretta M et al. Human SIR2 deacetylates p53 and antagonizes PML/p53 - inducedcellular senescence. EMBO J, 2002; 21 (10): 2383 - 2396
7Taylor DM, Maxwell MM, Luthi--Carter R, et al. Biological and potential therapeutic roles of sirtuin deaeetylases[J]. Cellular and Moleucular Life Sciences, 2008,65:4 000.
8Luo J, Nikolaev AY, Inai S, et at. Negative control of p53 by Sir2 alpha promotes cell survival under stress[J]. Cell, 2001,107:137.
9Cheng HL, Mostoslavsky R, Saito S, et al. Developmental defects and p53 hyperactylation in Sir2 homolog(SIRT1)-- deficient mice [J]. Proc Natl Acad Sci USA, 2003, 100: 10794.
10Li Y, Yokota T, Gama V, et al. Bax--inhibiting peptide protects cells from polyglutamine toxicity caused by Ku70 acetylation[J]. Cell Death Differ, 2007,14:2 058.