摘要
壳聚糖作为一种资源丰富的新型天然高分子化合物,一种理化性质优良的多糖化合物,具有组织相容性好、生物学活性多样、低毒性、易于吸收等特点,是一种良好的药物释放载体。文章综述了壳聚糖在作为药物缓释载体时的生物学特点、类型及其在临床上的应用,其中作为基因运载工具的应用是近年来国内外研究的热点。同时还展望了壳聚糖作为药物载体的发展前景。
As a resourceful, new and natural macromoleculer compound and a kind of polyose compounds, chitosan was considered as a good pharmaceutical releasing carrier for lots of properties, such as sound tissue compatibility, various biologic activity, low toxicity, easy absorption, etc. Here, the biological properties, types and clinical application of chitosan as drug controlled release carrier, particularly its application as gene carrier, were introduced. Besides, the directions for future development of chitosan as drug carrier were forecasted.
出处
《现代食品科技》
EI
CAS
2007年第7期98-100,共3页
Modern Food Science and Technology
关键词
壳聚糖
载体
基因运载
chitosan
carrier
gene carrier
