摘要
目的:采用GC法测定云威灵软胶囊中百里香酚、异丁酸百里香酯的含量。方法:色谱柱:100%DIMETHYL POLYSILOX ANE石英毛细管柱,30mm×0.25mm(SGE公司),柱温:160℃,汽化温度:220℃,检测器温度:200℃。载气为氮气,柱前压:6磅/英寸。,分流比为50:1,检测器:FID。结果:结果表明百里香酚在0.6~3.8g,g范围内具有良好的线性关系,异丁酸百里香酯在0.8~4.5峭范围内具有良好的线性关系,加样回收率:百里香酚为:99.07%,异丁酸百里香酯为:99.42%。结论:该方法简单迅速,结果准确,精密度好,可用于云威灵软胶囊的质量控制。
Objective: The gas chromatography(GC) method was used to determine the content of thymol and isobutyric acid thyme in Yunwei Capsule. Mehtod : The chromatography column was 100% DIMETHYL POLYSILOX ANE quartz capillary column with column temperature 160 ℃, vaporization temperature 220℃ and detector temperature 200 ℃. The carder gas was nitrogen, precolumn press was 6 pound/inch2, split ratio was 50 : 1, detector: FID. Result: The result indicated that thymol had a good linear relationship at the range of 0.6 - 3.8 μg, So do isobutyric acid thyme at the range of 0.8 -4.5μg, the spotting recovery was 99.07% in thymol, 99.42% in isobutyric acid thyme. Conclusion: The method is simple, accurate with good precision, can be used to control Yunweiling capsule.
出处
《中医药导报》
2007年第7期98-99,115,共3页
Guiding Journal of Traditional Chinese Medicine and Pharmacy