摘要
脑胶质瘤是最常见的神经系统原发肿瘤。放射治疗是目前脑胶质瘤综合治疗最重要的治疗手段之一。然而经过放射治疗以后,部分肿瘤又会复发。随着肿瘤干细胞学说的确立,神经肿瘤干细胞的成功筛选和分离,研究者开始对其生物学特性进行了一系列基础研究,从肿瘤干细胞角度解释其放射生物学行为。放射肿瘤学研究者探求从治疗上特异于杀伤神经肿瘤干细胞,靶向作用于其相关信号转导通路,以期能为临床诊疗提供新的思路,最终使恶性胶质瘤临床放射治疗受益。
Radiation therapy is one of the important treatment strategies for gliomas, the most common primary central nervous system tumors. However, tumor relapse is common after radiotherapy. With the successful sorting and isolation of the brain-tumor stem cells, the theory of brain-tumor stem cells is getting its recognition, Research on the biology of brain-tumor stem cells has been carried out to target the specific signaling pathway and specifically kill these cells.
出处
《中国神经肿瘤杂志》
2007年第2期142-146,共5页
Chinese Journal of Neuro-Oncology
