西宁地区儿童过敏性紫癜128例临床分析

CLINICAL ANALYSIS OF 128 CHILDREN WITH HEAOCH-SENONLEIN PURPURA AT XINING AREA

目的探讨西宁地区儿童过敏性紫癜(Henoch一Schonlein purpura,HSP)的临床特征。方法对128例过敏性紫癜患儿的发病特点、临床表现、肾损害相关因素等方面进行回顾性分析。结果发病季节:第1、2、3、4季度的发病率依次为32.03%、9.37%、7.04%、51.56%。诱因:感染占72.65%,药物过敏占10.94%,食物过敏占7.3%。肾脏症状发生率为26.56%。结论西宁地区HSP发病率以第1、4季度发病人数为多;发病诱因以感染为首要因素,结果有别于内地。HSP早期出现较多肾外症状,易发生肾损害。以腹痛为首发症状的HSP易误诊为急腹症。

Objective To study the clinical characteristics of children Henoch - Schonlein Purpura （HSP） in Xining area. Methods 128 cases HSP were studied and the patterns of onset, clinical manifestations, correlated factors of renal damage and the rare symptoms were analysed. Results Seasons and onset ： The onset percentage of the 1,2,3,4 quarter season were 32.03% ,9.37% ,7.04% ,51.56% respectively. Inducing factors： They were including infections （72.65%）, drug allergy （ 10.94% ）, food allergy （ 7.3% ）, some of them （ 26.56% ） showed symptoms of renal damage. Conclusion Morbidity of HSP was more in the first and the fourth quarter than that of the others. The most potant inducing factor was infection. There were many extrarenal symptoms during early phase in the HSP patients. Those with the rare symptoms tended to have renal damage. Those HSP whose first symptom was abdominal pain can be misdiagnosed as acute abdominal disease.