婴幼儿重症肺炎多巴胺、多巴酚丁胺心血管支持探讨

SUPPORT OF CARDIOVASCULAR FUNCTION WITH DOPAMINE AND DOBUTAMINE IN INFANT SEVERE PNEUMONIA

目的探讨多巴胺多巴酚丁胺、静脉持续泵入在婴幼儿重症肺炎时对心血管功能支持的早期干预作用和意义。方法婴幼儿重症肺炎患儿随机分为两组,治疗组入院在综合治疗的基础上予多巴胺和多巴酚丁胺(各5μg/kg×m in-1)静脉持续泵入,比较两组住院、临床症状缓解所需时间;动态观察两组患儿收缩压和心率的变化。结果治疗组较对照组住院、临床症状缓解所需时间明显缩短(P<0.01);两组12小时收缩压和心率监测无明显差异(P>0.05)。结论及早给予婴幼儿重症肺炎早期多巴胺、多巴酚丁胺心血管功能支持治疗可提高疗效,缩短病程。

Objective To study the early interventional effects in support of cardiovascular function through intravenous drip of dopamine and dobutamine in treating infant severe pneumonia. Methods The infant severe pneumonias were randomly divided into two groups. The treatment group was treated with intravenous drip of dopamine and dobutamine （Sug/kg· min^-1） on the basis of combined treatment until the complications of pneumonia were cured. The control group was treated with combined treatment. Two groups were compared in the time of their clinical symptoms alleviated and the change of their systolic pressures and heart rates was dynamically observed. Results Compared with the control group, the time of their clinical symptoms alleviated in treatment group was obviously shortened （P 〈0.01 ）, however, there were no significant change in their systolic pressures and heart rates in 12 hours between two groups（ P 〉0.05）. Conclusion The remedial effect of infant severe pneumonia can be improved through the early interventional measure with intravenous drip of dopamine and dobutamine for support of cardiovascular function.