先天性心脏病患儿血清CK-MB分析

Detection and analysis of CK-MB level in serum of children with congenital heart disease

目的观察先天性心脏病患儿血清磷酸肌酸激酶同功酶的变化。方法比较先天性心脏病儿及正常儿血清磷酸肌酸激酶同功酶水平,并进行统计学分析。结果磷酸肌酸激酶同功酶水平:①先天性心脏组高于正常对照组;②心力衰竭组高于非心力衰竭组;③青紫组高于非青紫组,且差异具有显著性,P值均小于0.01。结论先天性心脏病患儿本身存在缺陷、心力衰竭及血氧低,可加重心肌细胞损伤。

Objective To observe change in CK-MB level in serum of children with congenital heart disease. Methods The CK-MB level in serum of children with congenital heart disease and healthy children was detected and analyzed by statistics. Results （1）Compared with the control group, CK-MB level was higher in the congenital heart disease group（48.05 ±15.83 vs 27.56 ± 21, 34） ; （1）Compared with non-heart failure group, CK-MB level was higher in the heart failure subgroup（57.55 ± 13.35 vs 39.83 ± 15.74） ; （2）Compared with non- cyanosis subgroup, CK-MB level was higher in the cyanosis subgroup（62.28 ±16.36 vs 41.28 ±12.78 ）, All the differences were significant. Conclusion The cardiac muscle damages may exist in children with congenital heart disease, and heart failure and hypoxla can aggravate the damages.