摘要
应用PCR-RFLP技术检测福建地区167例2型糖尿病患者(其中80例合并糖尿病肾病)和62名健康对照者TGF-β1基因T29→C多态性,结果显示,C等位基因可能与糖尿病肾病发病相关。
The allele frequency and genotype distribution of the 29T→C polymorphism in TGF-β1 gene were studied in the groups of 62 normal control subjects and 167 type 2 diabetes patients, with or without diabetic nephropathy. Diabetes patients with C allele were susceptible to diabetic nephropathy than those without C allele.
出处
《中国糖尿病杂志》
CAS
CSCD
北大核心
2007年第7期416-417,共2页
Chinese Journal of Diabetes
关键词
糖尿病
2型
糖尿病肾病
转化生长因子Β1
多态性
限制性片段长度
Diabetes mellitus, type 2
Diabetic nephropathy
Transforming growth factor beta 1
Polymorphism, restriction fragment length
