钨钛磷稀土杂多酸盐的合成及其抗艾滋病病毒活性的研究

Studies on Synthesis and Anti HIV 1 Activity of Heteropoly Complexes of Tungstotianophosphates Containing Rare Earth Elements

合成了通式为ＬｎｘＨ［ＰＴｉ２Ｗ１０Ｏ４０］·ｘＨ２Ｏ（Ｌｎ＝Ｌａ、Ｃｅ、Ｐｒ、Ｎｄ、Ｓｍ、Ｅｕ、Ｇｄ、Ｔｂ、Ｙｂ、Ｌｕ）的稀土杂多配合物，通过ＩＲ、ＵＶ、３１Ｐ、１８３ＷＮＭＲ谱对其结构进行了表征。配合物抗艾滋病病毒（ＨＩＶ１）活性的研究表明。

The present paper reports nine new heteropoly compounds of tungstotianophosphates containing rare earth elements. i.e., Ln 2H[PTi 2W 10 O 40 ]· x H 2O(Ln=La, Ce, Pr, Nd, Sm, Gd, Tb, Yb, Lu). They were characterized by elemental analyses, IR, UV, 31 P, 183 W NMR. The experiments show that this kind of compounds are effective inhibitor with low toxicity and high anti HIV 1 activity.