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138例脑梗死与颈动脉粥样硬化关系的临床研究 被引量:6

Study on the correlation between cerebral infarction and carotid atherosclerosis
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摘要 目的:探讨脑梗死与颈动脉粥样硬化的关系。方法:对138例脑梗死患者及150例非脑血管病者行颈部血管彩色多普勒检查,比较两组间的颈动脉内-中膜厚度及斑块发生率。结果:脑梗死组颈动脉内-中膜明显厚于对照组(P<0.05)。脑梗死组斑块发生率(71.0%)明显高于对照组(37.2%)(P<0.05)。结论:颈动脉粥样硬化与脑梗死密切相关,是脑梗死不可忽视的危险因素。 Objective: To study the correlation between cerebral infarction and carotid atherosclerosis. Methods: Color Doppler Ultrasonography of the carotid artery were performed on 138 patients with cerebral infarction and 150 people without cerebrovascular diease. The intima-media thickness(IMT) of the posterial wall and plaques at carotid artery were studied. Results: The IMT in cerebral infarction patients were significantly thicker than that in control group (P 〈0.05). And the plaque presence of carotid artery was found 98/138(71.0%) in cerebral infarction , 55/150(37.2%) in control group. There was significant difference between two groups (P 〈0.05). Conclusion: Carotid atherosclerosis is correlated to cerebral infarction and is an important risk factor to cerebral infarction.
出处 《新疆医科大学学报》 CAS 2007年第6期575-577,共3页 Journal of Xinjiang Medical University
关键词 脑梗死 颈动脉粥样硬化 内-中膜厚度 cerebral infarction carotid atherosclerosis IMT
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  • 1周定标,Eric.,DL.颈动脉内膜切除治疗暂时性脑缺血[J].中华外科杂志,1989,27(12):743-745. 被引量:7
  • 2张贞耀,陈达光,陈玲,王华军,陈松苍.颈总动脉内径扩大与内膜—中层厚度是高血压合并动脉粥样硬化的两个重要标志[J].中国循环杂志,1996,11(6):337-341. 被引量:22
  • 3Hanyu M, Kume N, Ikeda T.VCAM-1 expression precedes macrophage infiltration into subendothelium of vein grafts interposed into carotid arteries in hypercholesterolemic rabbits-a potential role in vein graft atherosclerosis.Atherosclerosis, 2001, 158 (2):313-319
  • 4Dietrich H, Hu Y, Zou Y.Mouse model of transplant arteriosclerosis:role of intercellular adhesion molecule-1.Arterioscler Thromb Vasc Biol, 2000, 20 (2):343-352
  • 5Koyama H, Maeno T, Fukumoto S, Shoji T, Yamane T, Yokoyama H.Platelet P-selectin expression is associated with atherosclerotic wall thickness in carotid artery in humans.Circulation, 2003, 108 (5):524-529
  • 6Seye CI, Yu N, Jain R, Kong Q, Minor T, Newton J.The P2Y2 nucleotide receptor mediates UTP-induced vascular cell adhesion molecule-1 expression in coronary artery endothelial cells.J Biol Chem, 2003, 278 (27):24 960-965
  • 7Marin ML, Gordon RE, Veith FJ.Distribution of c-myc oncoprotein in healthy and atherosclerotic human carotid arteries.J Vasc Surg, 1993, 18 (2):170-176
  • 8Mills CJ, Northrup JL, Hullinger TG.Temporal expression of c-fos mRNA following balloon injury in the rat common carotid artery.Cardiovasc Res, 1996, 32 (5):954-961
  • 9Matsushita H, Morishita R, Aoki M.Transfection of antisense p53 tumor suppressor gene oligodeoxynucleotides into rat carotid artery results in abnormal growth of vascular smooth muscle cells.Circulation, 2000, 101 (12):1 447-452
  • 10Yasumoto H, Kim S, Zhan Y.Dominant negative c-jun gene transfer inhibits vascular smooth muscle cell proliferation and neointimal hyperplasia in rats.Gene Ther, 2001, 8 (22):1 682-689

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