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4项指标联合监测对急性心肌梗死的诊断价值 被引量:9

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摘要 目的探讨肌红蛋白(Mb)、心肌肌钙蛋白I(cTnI)、肌酸激酶同工酶(CK-MB)及超敏C-反应蛋白(hs-CRP)联合监测对急性心肌梗死(AMI)的诊断价值。方法采用化学发光法测定68例急性心肌梗死患者及60例其他原因引起的胸痛患者(作为对照组)胸痛发作24h内Mb、cTnI、CK-MB、hs-CRP。采用免疫透射比浊法,比较它们对AMI诊断的敏感性和特异性,并进行组合。结果在入院后24h内Mb、cTnI、CK-MB、hs-CRP对AMI的敏感性分别为100%、97.1%、92.6%和94.1%,特异性分别为86.7%、98.3%、93.3%和92.6%;cTnI阳性预测值(98.5%)最高,Mb阴性预测值(100%)最高。结论Mb、cTnI、CK-MB、hs-CRP联合监测,相互补充,可提高对AMI的敏感性和特异性同时对再梗死发生、预后及观察疗效具有重要意义。
作者 杜开春
出处 《检验医学与临床》 CAS 2007年第8期736-737,共2页 Laboratory Medicine and Clinic
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