摘要
目的研究心房颤动(房颠)患者的临床特点和血栓栓塞及抗凝治疗的现状。方法选择我院1999年12月至2001年12月诊断为房颤的559例患者的住院病例进行回顾性分析,并于2004年11~12月随访471例,随访率87.06%。结果血栓栓塞事件中,以缺血性脑卒中多见。在入选病例中,接受抗栓治疗者达80.68%,华法林治疗INR多为1.5~2.0;阿司匹林剂量多为100 mg/d。在非瓣膜性房颤的患者中,13.52%有发生血栓栓塞危险因素的患者出院时未给予任何抗栓治疗;在出院后的3~4年中,有19.36%的患者因为担心出现出血事件而自行停止抗凝治疗。结论提示目前房颤抗栓治疗应得到临床医师及患者的充分认识和重视,提高患者的依从性。
Objective To study the clinical characteristics and the current status of thromboembolism and the antithromboric therapy in patients with atrial fibrillation ( AF). Methods Retrospective analysis of hospital records was taken from 559 patients with AF who were hospitalized from Dec. 1999 to Dec. 2001. The follow-up was carried out from Nov. to Dec. in 2004 and the rate of follow-up was 87.06%. Results The most common thromboembolic event was ischemic stroke, Over 80.68% patients received antithrombotic therapy. Most of the rages of INR were 1.5 - 2.0 among the patients treated with warfarin. The main dose of aspirin was 100mg/d. 13.52% of NVAF patients with the risk factors of thromboembolism hadn't received any antithrombotic agents. 19.36% patients hadn't taken orally warfarin in the next 3 - 4 years because of being afraid of hemorrhage. Conclusion The antithrombotic therapy needs to be sufficiently recognized by patients and physicians so as to improve the compliance of patients.
出处
《中国医药》
2007年第9期528-530,共3页
China Medicine
关键词
心房颤动
血栓栓塞
抗凝治疗
Atrial fibrillation
Thromboembolism
Antithrombotic therapy