广东省汕头市澄海区农村人群症状性骨关节炎危险因素研究

Associated risk factors of osteoarthritis in rural population of Chenhai District of Shantou

目的探讨广东省汕头地区农村人群症状性骨关节炎(OA)的相关危险因素,以提高OA的综合防治水平。方法对广东省汕头市澄海区某乡2350名16岁以上居民进行流行病学调查。采用Logistic回归分析,观察年龄、性别、体质指数(BMI)、腰臀比(WHR)、职业等因素对OA的影响。结果症状性OA患病率为10.7%,男女患病率分别为8.8%与12.4%;患病率随年龄增加呈升高趋势;OA受累部位以腰椎、膝、颈椎常见,手和髋关节少见。Logistic回归分析显示,增龄、超重和肥胖、职业是腰椎OA的相关危险因素;增龄、超重和肥胖是膝OA的相关危险因素;增龄、职业是颈椎OA的相关危险因素;增龄是手OA的相关危险因素。结论广东省汕头地区农村人群症状性OA受累部位以腰椎、膝、颈椎常见,增龄、超重和肥胖、职业可能是OA的危险因素,不同部位OA的相关危险因素亦有所不同,应加强OA的综合防治。

Objective To investigate the risk factors of osteoarthritis （ OA ） in the rural population of Shantou area aiming at improving the preventive level. Methods A total of 2350 subjects aged ≥16 years in a village of Chenghai District,Shantou area,were surveyed. Significant variables such as age, sex,body mass index （BMI）, Waist-to-hip ratio （ WHR ）, and occupation, were included in logistic regression model for further analysis. Results Prevalence rate of OA in this rural population was 10.7%, and the prevalence in women and in men werel2.4% and 8.8% respectively,with a tendency of being increased with age. The commonly seen sites of OA involvement were lumbar spine, knee joint and cervical spine, and other sites such as hands and hips were rarely affected. Logistic regression revealed that age, BMI and occupation were significantly associated with lumbar OA. Age and BMI were significantly associated with knee OA. Age and occupation were significantly associated with cervical OA. And age was significantly associated with hand OA. Conclusion In Shantou rural area,the common sites of OA involvement are lumbar spine,knee joint and cervical spine,whereas other sites such as hands and hips are rarely affected. Aging,overweight, and occupation might be the associated risk factors of OA. And the associated risk factors may be varied with different sites of OA. Integrate control of OA should be enhanced.