摘要
以氟哌酸为原料，合成了5种尚未见报道的衍生物，经体外抗菌试验验证，部分衍生物的活性优于氟哌酸；并对其结构与活性的关系作了探讨。
Five norfloxacin derivatives were synthesized. Some derivatives possessed better antibacterial activity aHainst five bacteria in vitro than norfloxacin. The strucure-activity relationship of them has been studied.
出处
《华西药学杂志》
CAS
CSCD
北大核心
1997年第1期14-16,共3页
West China Journal of Pharmaceutical Sciences
关键词
氟哌酸衍生物
抗菌活性
Norfloxacin derivatives Synthesis Antibacterial activity
