早产儿奶摄入量与坏死性小肠结肠炎发生及体质量增长关系的探讨

The relationship of feeding volume to necrotizing enterocolitis and increasing body weight in premature infants.

目的 探讨早产儿奶摄入量与坏死性小肠结肠炎（NEC）发生及体质量增长之间的关系。方法 将223例早产儿随机分为2组，对照组逐日每次奶量递增为0．5～1．0ml，观察组按每日20ml／（kg·d）奶量进行个体化喂养。观察在喂养控制摄入情况下，发生坏死性小肠结肠炎的基本情况，及体质量增长情况。结果 对照组发生NEC2例，观察组3例，经统计学分析，两组之间NEC发生率无明显差异（P〉0．05）；观察组体质量增长快及住院天数也明显缩短，差异有统计学意义（P〈0．05）。结论 根据体质量变化情况制定每日摄入量，不会增加NEC的发生率，但可维持正常体质量的增长，并可以缩短早产儿的住院天数。

Objective To explore the relationship of feeding volume to neerotizing enteroeolitis （NEC） and increasing body weight in premature infants. Methods A total of 223 premature infants were randomly divided into two groups. Feeding volume increased 0.5 ～1 ml day by day in control group. The infants in the other group were fed 20ml/（ kg ·d）. The incidence of NEC and the increase of body weight were observed and compared between the two groups. Results The results showed that 2 NEC eases were found in control group,while 3 NEC eases were found in observation group. There was no significant difference in the incidence of NEC between the two groups. However, significant differences were found in body weight increase and average hospitalization time between the two groups. Conclusion Feeding 20ml/ （ kg·d） may shorten hospital stay and increase body weight of premature infant without increasing the incidence of NEC.