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瑞芬太尼复合丙泊酚麻醉在小儿眼科手术中的应用

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摘要 目的观察瑞芬太尼复合丙泊酚在小儿眼科手术中的应用,了解并证实其起效快苏醒快的优越性。方法行小儿眼科手术30例,随机分为A、B两组。诱导时A组用瑞芬太尼1μg/kg,B组则用芬太尼5μg/kg。维持用药:A组患者用微量泵经静脉持续泵入瑞芬太尼〔开始速度0.25μg/(kg.min),逐渐减量至0.1μg/(kg.min)〕和丙泊酚〔开始速度8~10mg/kg/h,逐渐减量至5~7mg/(kg.h)〕),B组则按需间断追加芬太尼2~3μg/kg,并同A组一样经静脉持续泵入丙泊酚。观察记录苏醒时间、术后恢复评价指标即数字-符号替换测试评分DSST(digit-symbolsubstitutiontestscore),并计算DSST恢复率:术后DSST评分/术前DSST评分×100%,记录麻醉药用量。结果苏醒时间A组显著短于B组,且A组术后DSST评分显著高于B组。A组瑞芬太尼用量(650±394)μg,B组芬太尼用量(458±157)μg。A组丙泊酚用量(150.4±33.9)mg明显少于B组的(173.7±46.4)mg。结论瑞芬太尼复合丙泊酚全凭静脉麻醉显著缩短了苏醒时间,显著提高了术后DSST恢复率,术后认知功能恢复较好,恢复清醒程度较高。特别适合切口小创伤小、术后疼痛较轻、无需术后镇痛的眼科手术。
出处 《医药论坛杂志》 2007年第12期103-104,共2页 Journal of Medical Forum
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