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胃肠道间质瘤的研究进展 被引量:4

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摘要 胃肠道间质瘤(GIST)是胃肠道最常见的间叶源性肿瘤。GIST中C-kit基因突变,导致KIT酪氨酸激酶持续活化,细胞增殖分化失控,最终导致肿瘤。CD117的表达,对GIST的诊断有重要价值。格列卫(ima-tinib)为酪氨酸激酶抑制剂,治疗GIST取得了良好效果。
出处 《医药论坛杂志》 2007年第12期119-121,共3页 Journal of Medical Forum
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