神经外科医院感染的特点及细菌耐药动态

Neurosurgical Hospital Infection Characteristics and Bacterial Resistance Condition

目的了解神经外科的医院感染特点及其细菌的耐药情况,为临床合理使用抗菌药物提供参考信息。方法以主动监测与系统回顾相结合的方法,对2005年全年入住神经外科的880例患者的临床资料进行统计、分析、评判。结果神经外科的医院感染例次率是16.36%,显著高出同期的医院平均感染率9.18%;神经外科医院感染的病原菌以G-菌为主,感染部位以泌尿道感染为首占44.44%,其次是下呼吸道感染占35.42%;共检出大肠埃希菌60株(20.2%)、屎肠球菌(D群)34株(11.44%)、鲍氏不动杆菌25株(8.42%)、铜绿假单胞菌25株(8.42%)、肺炎克雷伯菌18株(6.06%)等。结论全面系统地监测神经外科医院感染的特点及其细菌耐药动态,对临床合理使用抗菌药物有重要的参考意义。

OBJECTIVE To undersand neurosurgical hospital infection characteristics and bacterial resistance, and to provide reference information for the rational use of antibacterial drugs in clinics. METHODS Using the combined methods of initiative monitoring and recalling system to carry on the clinical informationsr statistics, the analysis and the judgment for the 880 inpatients in the neurosurgery department in 2005. RESULTS The rate of neurosurgical hospital infection was 16.36%, significantly higher than the hospital average rate （9.18%） at the same period. Neurosurgical hospital infection pathogens were mainly Gram-negative bacteria. Infection sites occurred mainly in urinary tract （44.44%）, followed by lower respiratory tract （35.42%）. Sixty strains were Escherichia coli （20.2%）, 34 strains （11.44%） for Enterococcus faecium （D group）, 25 strains （8.42%） for Acinetobacter baumannii, 25 strains （8.42 %） for Pseudomonas aeruginosa, and 18 strains （6.06 %） for Klebsiella pneumoniae. CONCLUSIONS Systematic monitoring of neurosurgieal hospital infection characteristics and dynamics of bacterial resistance has important clinical reference significance to the rational use of antibacterial drugs.