努力提高多发性骨髓瘤的基础和临床研究水平
摘要
多发性骨髓瘤(multiple myeloma,MM)是浆细胞的恶性克隆增生性疾病,以骨髓中大量克隆性浆细胞的增生和积聚,并分泌单克隆的免疫球蛋白(M蛋白)或其片段,同时伴有广泛的溶骨病变和/或骨质疏松为特征。尽管人们对于MM的认识已有150年的历史,但到目前为止MM仍然是一种不可治愈的疾病。
出处
《国际输血及血液学杂志》
CAS
2007年第4期289-290,共2页
International Journal of Blood Transfusion and Hematology
参考文献9
-
1Guido T. Multiple myeloma and other plasma disorders [M]// Hoffman R. Hematology-basic principles and practice. 4th ed. Elsevier, 2005: 1501-1505.
-
2Portier M, Lees D, Caron E, et al. Up-regulation of interleukin (IL)-6 receptor gene expression in vitro and in vivo in IL-6 deprived myeloma cells. FEBS Lett, 1992, 302 ( 1 ) : 35-38.
-
3侯健 赵君 孔宪涛.IL-6与MM增殖机制[J].中华血液学杂志,1992,13:533-535.
-
4Fonseea R, Barlogie B, Bataille R, et al. Genetics and eytogeneties of multiple myeloma:a workshop report. Cancer Res,2004,64 (4) : 1546-1558.
-
5Kumar S, Witzig TE, Timm M, et al. Bone marrow angiogenic ability and expression of angiogenie eytokines in myeloma: Evidence favoring loss of marrow angiogenesis inhibitory activity with disease progression. Blood, 2004,104 (4) : 1159-1165.
-
6Child JA, Morgan GJ, Davies FE, et al. High-dose chemotherapy with hematopoietie stem-cell rescue for multiple myeloma. N Engl J Med, 2003,348 (19) : 1875-1883.
-
7Dimopoulos MA, Anagnostopoulos A, Weber D. Treatment of plasma cell dyscrasias with thalidomide and its derivatives. J Clin Oncol, 2003,21 (23) :4444-4454.
-
8Richardson PG, Sonneveld P, Schuster MW, et al. BOrtezomib or high-dose dexamethasone for relapsed multiple myeloma. N Engl J Med,2005,352(24) :2487-2498.
-
9Harousseau JL, Attal M, Leleu X, et al. Bortezomib plus dexamethasone as induction treatment prior to autologous stem cell transplantation in patients with newly diagnosed multiple myeloma : results of an IFM phase Ⅱ study. Haematologica, 2006, 91(11) :1498-1505.
-
1侯健.加强对多发性骨髓瘤的基础和临床研究[J].武警医学,2003,14(11):645-646.
-
2李勇华,侯健,王东星,袁振刚,陈玉宝,傅卫军.沙立度胺治疗多发性骨髓瘤疗效影响因素分析[J].中华内科杂志,2006,45(7):587-589. 被引量:1
-
3周国彬.万珂治疗多发性骨髓瘤诱发周围神经炎病变患者护理体会[J].中国中医药现代远程教育,2013,11(11):110-110. 被引量:4
-
4周小伟,周亚新.VAD方案治疗难治性多发性骨髓瘤疗效观察[J].河北医药,2002,24(7):603-603.
-
5赵薇,范菊红,浦晓瑜.硼替佐米治疗多发性骨髓瘤致周围神经炎病变的护理体会[J].内蒙古中医药,2013,32(36):162-162. 被引量:4
-
6王丽红,温影.护理干预对万珂治疗多发性骨髓瘤诱发周围神经炎病变患者护理体会[J].中国实用医药,2013,8(16):234-234. 被引量:7
-
7王婷婷,徐剑,杨仁池.多发性骨髓瘤的预后相关因素[J].中华血液学杂志,2003,24(10):555-557. 被引量:9
-
8马静玲,冯怿霞,揭素铭,许丽梅.硼替佐米治疗多发性骨髓瘤的护理[J].护理实践与研究,2009,6(3):55-56. 被引量:1
-
9闫建丽,高峰杰,耿红旭,梅志敏.多发性骨髓瘤10例误诊分析[J].中原医刊,2007,34(10).
-
10郭旖旎.慢性粒细胞白血病急变期的护理体会[J].中国疗养医学,2010,19(3):236-236.