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川崎病发病机制研究进展 被引量:27

Development of Kawasaki Disease Pathogenesis
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摘要 川崎病(KD)主要累及中小动脉,特别是冠状动脉,可形成冠状动脉瘤或扩张,冠状动脉狭窄或血栓,甚至导致心肌梗死,是儿童后天性心脏病常见的原因。近年来临床和流行病学资料表明,KD的发病与细菌超抗原致病学说、T细胞介导的免疫应答、血管内皮功能障碍、血小板活化等有关。KD是一种免疫介导的全身性血管炎。
出处 《实用儿科临床杂志》 CAS CSCD 北大核心 2007年第13期1037-1040,共4页 Journal of Applied Clinical Pediatrics
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参考文献15

  • 1Meissner HC,Leung DY.Superantigens,conventional antigens and the etiology of Kawasaki syndrome[J].Pediatr Infect Dis,2000,19(2):91-94.
  • 2Iemure M,Ishii M,Sugimura T,et al.Long consequences of regressed coronary aneurysms after Kawasaki disease:Vascular wall morphology and function[J].Heart,2000,83(3):307-311.
  • 3Brogan PA,Shan V,Klein N,et al.Vbeta-restricted T cell adherence to endothelial cells:Α mechanism for superantigen-dependent vascular injury[J].Arthritis Rheum,2004,50(2):589-597.
  • 4Onouchi Y,Onoue S,Tamari M,et al.CD40 ligand gen and Kawasaki disease[J].Eur J Hum Genet,2004,12(12):1062-1068.
  • 5Okada Y,Shinohara M,Kobayashi T,et al.Effect of corticosteroids in addition to intravenous gamma globulin therapy on serum cytokine levels in the acute phase of Kawasaki disease in children[J].J Pediatr,2003,143(3):363-367.
  • 6Chang RK.Epidemiologic characteristics of children hospitalized for Kawasaki disease in California[J].Pediatr Infect Dis J,2002,21(12):1150-1155.
  • 7Holman RC,Shahriari A,Effler PV,et al.Kawasaki syndrome hospitalizations among children in Hawaii and Connecticut[J].Arch Pediatr Adolesc Med,2000,154(8):804-808.
  • 8Genizi J,Miron D,Spiegel R,et al.Kawasaki disease in very young infants:High prevalence of atypical presentation and coronary arteritis[J].Clin Pediatr(Phila),2003,42(3):263-267.
  • 9Chua PK,Melish ME,Yu Q,et al.Elevated levels of metalloproteinases 9 and tissue inhibitor of metalloproteinase 1 during the acute phase of Kawasaki disease[J].Clin Diagn Lab Immunol,2003,10(2):308-314.
  • 10Takeshita S,Tokutomi T,Kawase H,et al.Elevated serum levels of matrix metalloproteinase-9(MMP-9)in Kawasaki disease[J].Clin Exp Immunol,2001,125(2):340-344.

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