非痴呆型血管性认知障碍患者的神经心理学研究

The Research of the Patients with Vascular Cognitive Impairment no Dementia in Terms of Neuropsychology

目的探讨非痴呆型血管性认知障碍患者(VCIND)的神经心理学特点。方法对42例VCIND患者和38例健康对照者进行MMSE、日常生活行为量表、Preffer门诊患者功能缺损调查表、画钟测验、临床痴呆评定量表、Hachinski缺血指数、流调用抑郁自评量表检查。结果神经心理学检查显示VCIND患者和对照组相比,在MMSE总分及其地点定向、时间定向、注意力和计算力、短程记忆、书写能力、结构能力各亚项和执行功能方面比较有显著性差异(P<0.05)。结论CDT与MMSE合用可以用于认知功能损害的早期筛查。

Objective This paper is to investigate the characteristics of the patients with Vascular Cognitive Impairment of None dementia （VCIND） in terms of neuropsychology. Methods 42 patients with VCIND and 38 normal controls were examined with the neuropsychological test, including： mini -mental state examination （MMSE）, activities of daily living scale （ADL）, Preffer outpatient disability questinnair （ POD）, clock drawing test （CDT） and clinical dementia rating scale （ CDR）, Hachinski ischaemic scale （ HIS）, and center for epidemiological studiesdepression scale （ CES - D） . Results The scores of MMSE, CDT in the VCIND group were significantly lower than those in the control group （ P 〈 0. 05 ） ; the scores in the VCIND group, as far as place orientation, time orientation, attention calculation, verbal recognition memory, writing ability and structure ability were concerned, were significantly lower than those in the normal control group （P 〈 0. 05） . Conclusions The combination of CDT and MMSE can be used for early screening of cognitive impairment.