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急性冠脉综合征患者血清脂蛋白(a)水平变化的临床意义

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摘要 目的:观察急性冠脉综合征(ACS)患者血清脂蛋白a[Lp(a)]水平变化。方法:对144例ACS(ACS组)与74例稳定冠心病患者(对照组)进行回顾性分析,比较两组的Lp(a)水平,并同时观察两组血脂、高敏C反应蛋白(Hs-CRP)水平。结果:ACS组血清Lp(a)水平较对照组显著升高(P<0.05),同时Hs-CRP水平在ACS组亦明显升高(P<0.05),常规血脂4项总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)水平两组无明显差异(P>0.05),ACS组中不稳定型心绞痛组和急性心肌梗死组(AMI)LP(a)水平无明显差异(P>0.05)。结论:LP(a)可能在ACS发病中起促进作用,并且可能与Hs-CRP一样,是一项敏感的急性时相蛋白,可以反映冠状动脉粥样硬化斑块的不稳定性,预测ACS的发生。
作者 高英 韦金儒
机构地区 广西医科大学第五附属医院心内科
出处 《广西医科大学学报》 CAS 北大核心 2007年第3期407-409,共3页 Journal of Guangxi Medical University
关键词 脂蛋白A 急性冠脉综合征 高敏C反应蛋白
分类号 R692 [医药卫生—泌尿科学]
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参考文献7

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二级参考文献8

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广西医科大学学报
2007年 第3期

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