6Illum L,Farraj NF,Critchley H,et al.Enhanced nasal absorption of insulin in rats using lysophosphatidycholine[J].Int J Pharm,1989,57(1):49-54
7Marlin GP, Marriott C, Kellaway IW.Direct effect of bile salts and phospholipids on the physical properties of mucus[J]. Cut, 1978, 19(2) : 103- 107.
8Illum L, Fisher AN, Jabbed-Gill I,et al. Bioadhesive starch microspheres and absorption enhancing agents act synergistically to enhance the nasal absorption of polypeptides[J]. Int J Pharm, 2001, 222(1):109-119.
9Illum L,Farraj NF,Davis SS,et al.Investigation of the nasal absorption of biosynthetic human growth hormone in sheep-use of a bioadhesive microsphere delivery system[J].Int J Pharm,1990,63(3):207-211
10Chandler SC,, Thomas NW, Illum L. Nasal aimrption in the rat,Ⅲ. Effect of lysophospholipids on insulin absorption and nasal histology[J].Pharm Res, 1994, 11(11):1623- 1630.
8Hinchcliffe M, Ilium L. lntranasal insulin delivery and therapy [ J]. Adv Drug Deliv Rev, 1999,35 : 199.
9Khafagy ES, Morishita M, Onuki Y,et al. Current challenges in non-invasive insulin delivery systems: A comparative review[ J]. Adv Drug Deliv Rev ,2007,59 : 1521.
10Varshosaz J, Sadrai H, Heidari A. Nasal Delivery of Insulin Using Bioadhesive Chitosan Gels [ J ]. Drug Delivery, 2006, 13 : 31.
