不同病因早产儿预后研究

The study of premature infants prognosis with different cause of disease

目的:探讨不同病因对早产儿早期运动及智能发育的影响。方法:将148例早产儿按不同病因分自然早产组47例、医源性早产组56例和胎膜早破早产组45例3组,纠正胎龄足月时行新生儿神经行为(NBNA)、6月时行婴幼儿发育智能(CDCC)测试检查,并进行比较。结果:3组孕周和出生体重无明显差异(P>0.05)。以NBNA评分>35分者为正常,自然早产组、医源性早产组、胎膜早破早产组3者相比无显著性差异(P>0.05)。纠正胎龄6月CDCC测试,以PDI和MDI测试在85分以上为正常,自然早产组PDI、MDI正常率最高,与医源性早产组相比有显著性差异(P<0.05),与胎膜早破早产组相比无显著性差异。结论:早产儿的预后与早产病因相关,在早期运动和智能发育方面自然早产预后优于医源性早产组和胎膜早破早产组。

Objective： To explore the effect of different causes of disease to the preterm infant early time movement and intelligence growth. Methods： 148 premature infants were divided into three groups, according to different cause of disease, mark of natural premature delivery forms 47 examples, medicine source premature delivery 56 examples and preterm premature rupture of the membranes （PPROM） delivery forms 45, each group, correct fullterm gestational aged new born did neonatal behavioral neurological assessment （NBNA）, do the CDCC babies and infants intelligence growth test and comparison after six months. Results： NBNA grading were regular when greater than 35 marks. Being compared with each other, the natural premature delivery group, medicine source nature premature delivery group and PPROM group were no significant difference （P〉0.05） . Correct the CDCC 6 -month padding age testing. Be regular with PDI and the MDI testing above 85 marks. Natural premature delivery forms PDI, MDI regular rate are best than medicine source premature delivery forms and PPROM, there was significant difference between natural premature delivery forms and medicine source premature delivery （P 〉0. 05）, there was no significant difference between natural premature delivery forms and PPROM （P 〉 0. 05 ） . Conclusion： Preterm infant prognosis is relevant to the delivery cause. In the field of early phase motion and intelligence growth, natural premature delivery group is better than medicine source premature delivery group and PPROM.