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百日咳毒素和丝状血凝素的纯制和检测现况 被引量:2

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摘要 介绍了百日咳毒素和丝状血凝素的分离纯化及纯度、活性检定的方法。
作者 秦力 何长民
出处 《微生物学免疫学进展》 1997年第1期87-89,共3页 Progress In Microbiology and Immunology
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  • 1刘国安,杨晓明,葛瑞昌,何长民.百日咳毒素的等电点测定及层析分离[J].西北师范大学学报(自然科学版),2004,40(4):68-70. 被引量:2
  • 2杨瑜(综述),朱为(审校).百日咳毒素在疫苗中的研究现状及应用[J].国际生物制品学杂志,2007,30(4):156-159. 被引量:2
  • 3Ivanoff B, Robertson SE. Pertussis: a worldwide problem. Development in Biological Standardization, 1997, 89: 3-13.
  • 4Ozcengiz E, Ktlinc K, Buyuktamr O, et al. Rapid purification of pertussis toxin (PT) and filamentous hemagglutinin (FHA) by cation-exchange chromatography. Vaccine, 2004, 2202): 1570-1575.
  • 5Gillenius P, Jaatmaa E, Askelof P, et al. The standardization of an assay for pertussis toxin and antitoxin in microplate culture of Chinese hamster ovary cells. J Biol Stand, 1985, 13(1): 61-66.
  • 6Sheu GC, Wo YYP, Yao SM, et al, Characteristics and potency of an acellular pertussis vaccine composed of pertussis toxin, filamentous hemagglutinin, and pertactin. J Microbiol Immunol Infect, 2001, 34(4): 243-251.
  • 7Sekura RD, Fish F, Manclark CR, et al, Pertussis toxin-affinity purification of a new ADP-ribosyltransferase. J Bio Chem, 1983, 258(23): 14647-14651.
  • 8Tamura M, Nogimori K, Murai S, et al. Subunit structure of islet-activating protein, pertussis toxin, in conformity with the A-B model. Biochemistry, 1982, 21(22): 5516-5522.
  • 9Arai H, Sato Y. Separation and characterization of two distinct hemagglutinins contained in purified leukocytosispromoting factor from Bordetella pertussis. Biochim Biophys Acta, 1976, 444(3): 765-782.
  • 10Yajima M, Hosoda K, Kanbayashi Y, et al. Islets-activating pro- tein (IAP) in Bordetella pertussis that potentiates insulin secre- tory responses of rats. Purification and characterization[J]. J Bio- chem, 1978,83 (1) : 295-303.

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