摘要
以１龄性腺发育中期鲤鱼为材料，采用腹腔（ｉ．ｐ）注射的方法，研究不同的下丘脑肽和神经递质对鲤鱼促性腺激素（ＧｔＨ）和生长激素（ＧＨ）分泌的影响。结果表明：促甲状腺激素释放激素（ＴＲＨ）、Ｌ－多巴（Ｌ－ＤＯＰＡ）、甲基睾酮（ＭＴ）、γ－氨基丁酸（ＧＡＢＡ）、促黄体素释放激素类似物（ＬＨＲＨ－Ａ）和三碘甲状腺原氨酸（Ｔ３）都能显著刺激ＧｔＨ的分泌，但最大效应时间各不相同。ＴＲＨ和ＬＨＲＨ－Ａ能促进ＧＨ的分泌，Ｌ－ＤＯＰＡ、ＭＴ、ＧＡＢＡ对血清ＧＨ水平没有明显影响；Ｔ３则对ＧＨ分泌有一定的抑制作用。这说明鲤鱼ＧｔＨ和ＧＨ的分泌除了受各自的下丘脑释放因子和释放抑制因子的双重神经内分泌调控外，还受多种其它相同和不同调节因子的影响，也反映了鲤鱼ＧｔＨ和ＧＨ分泌的神经内分泌调控的复杂性。
Effects of different hypothalamic peptides and neurotransmitter on gonadotropin and growth hormone secretion in 1-year common carp at midrecrudenceses indicated that TRH, L-DOPA, MT, GABA, LHRH-A and T 3 could significantly stimulate GtH secretion, but their affecting time and tone were different from each other. TRH and LHRH-A also have GH stimulatory actions. No effects have been found of L-DOPA, MT and GABA on serum GH secretion; T 3 has inhibitory effect on GH release.
基金
国家自然科学基金
