临床分离变形杆菌的耐药性检测及分析

The resistance in proteus isolates

目的了解临床分离变形杆菌的耐药性。方法纸片扩散法(K-B法)测定菌株对常用抗菌药物的敏感性。结果变形杆菌对氨苄西林、头孢呋辛、环丙沙星、氨苄西林/舒巴坦的耐药率分别为66.7%、41.7%、25.0%、8.3%;对亚胺培南、阿米卡星、替卡西林、头孢噻肟、头孢他啶的耐药率均为0%。结论临床分离变形杆菌对第三代头孢菌素、亚胺培南敏感性高,氨苄西林、第二代头孢菌素耐药率较高。

Aim To investigate the resistance in proteus isolates.Methods The susceptibility test was performed by disk diffusion method.Results The resistance rate to ampicillin,cefuroxime,ciprofloxacin,and ampicillin/subactam was 66.7%,41.7%,25.0% and 8.3%,respectively.The resistance rate to imipenem,amikacin,cefotaxime,ceftazidime,and ticarcillin was 0%.Conclusion Proteus isolates are highly susceptible to the third generation cephalosporins and imipenem,and the resistance rate to ampicillin,cefuroxime is high.