欣母沛治疗产后出血42例临床研究

Clinical study of 42 cases of postpartum hemorrhage by using hemabate

目的：观察欣母沛治疗宫缩乏力所致产后出血的临床疗效。方法：我院从2004年1月-2006年8月因宫缩乏力所致产后出血123例,其中42例患者在采用缩宫素、米索前列醇和葡萄糖酸钙治疗无效后,加用欣母沛宫体注射或臀部深层肌肉注射,15min后视效果可重复使用。结果：42例患者,41例有明显效果,有效率97.6%,1例无效,后并发DIC,改行次全子宫切除术。结论：欣母沛治疗宫缩乏力性产后出血效果显著,越早使用,效果越好。

Objective： To observe the clinical effect of Hemabate for controlling atonic postpartum hemorrhage. Methods： From January 2004 to August 2006, there were 123 cases of atonic postpartum hemorrhage, of which 42 patients , after failing to respond to medical treatment with oxytocin, Misprostol and calcicum gluconate, 250p.g Hemabate was injected intrauterinely or buttock deep intramuscular injection, and it could be reused after 15 minutes according to the efficacy. Results： There were obvious efficacy in 41 cases, the effective rate was 97. 6%. One patient failed, of which was complicated by disseminated intravascular coagulation （DIC）, and the patient was altered to perform subtotal hysterectomy. Conclusion： Hemabate is very effective for treatment of severe atonic postpartum hemorrhage. The earlier the usage of Hemabate, the better the efficacy.