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虎杖中白藜芦醇的稳定性研究 被引量:17

Study on the Stability of Resveratrol in Rhizoma Polygoni Cuspidati
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摘要 目的:全面评价虎杖中白藜芦醇的稳定性。方法:使用物理的、化学的和生物的方法,人为增加各影响因素的影响强度,然后分析对比其影响效应而得出判断。结果:经光、干热、湿热和氧化处理的虎杖,其白藜芦醇的含量均大幅度下降;经酸碱处理的虎杖,只有用氢氧化钠处理pH=11的样品测得的含量有所提高;消除虎杖所含活性微生物的样品测得的含量没有增加。结论:在虎杖中,白藜芦醇对光、干热、湿热和氧化剂均敏感;虎杖所含活性微生物对其白藜芦醇的影响不大;酸性处理对其无益;碱化生成钠盐能提高其白藜芦醇的溶解性和稳定性。 Objective: The stability of resveratrol in Rhizoma Polygoni Cuspidati is evaluated all-roundly. Methods: We not only increase influence intensity by physical, chemical and biological methods but also parallel analyzing the influence results to elicit the opinions. Results : The content of resveratrol is declied greatly by lighting, heating, wet-heating or oxidizing. The content is increased in Rhizoma Polygoni Cuspidati treated with acid or alkali only using sodium hydroxide until pH = 11. The content is not increased when its own activated microbe is destroyed. Conclusion: Resveratrol is unstable against light, heat, wet-heating and oxidizer. Its own activated microbe has not influenced to it. It has not benefit with acidification. Its solubility and stability increase formed sodium salt with basification.
出处 《中药材》 CAS CSCD 北大核心 2007年第7期805-807,共3页 Journal of Chinese Medicinal Materials
基金 陕西科技大学自然科学基金项目(ZX04-20)
关键词 虎杖 白藜芦醇 稳定性 Rhizoma Polygoni Cuspidati Resveratrol Stability
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  • 1冯永红,许实波.白藜芦醇药理作用研究进展[J].国外医药(植物药分册),1996,11(4):155-157. 被引量:109
  • 2杨秀贤,王昕,吴寿金.从虎杖中提取大黄素的生产工艺[J].中草药,1996,27(2):87-87. 被引量:11
  • 3GANINI S J,HIRNTHI J,EUNG S L,et al.Kinase inhibitors from Polygonum cuspidatum[J].J Natral Prod,1993,56(10):1 805-1 810.
  • 4SIEMANN E H,CREASY L L.Concentration of the phytoalexin resveratrol in wine[J].Am J Enol Vitic,1992,43(1):49-52.
  • 5BERTELLI A A E,GIOVANNINI L,GIANNESSI D,et al.Antiplatelet activity of synthetic and natural resveratrol in red wine[J].Office International de la Vigne et du Vin,1995,17(1):1-6.
  • 6PACE-ASCIAK C R,HAHN S E,DIAMANDIS E P,et al.The red wine phenolics trans-resveratrol and quercetin block human platelet aggregation and eicosanoid synthesis:Implications for protection against coronary heart disease[J].Clin Chimica Acta,1995,235(2):207-219.
  • 7MISHIANG J,LINING C,UDEANI G O,et al.Cancer chemopreventive activity of resveratrol,a natural product derived from grapes[J].Science,1997,275(1):218-220.
  • 8BURKHARDT S,REITER R J,TAN D X,et al.DNA oxidatively damaged by chromium(Ⅲ) and H2 O2 is protected by theantioxidants melatonin,N(1)-acetyl-N(2)-fomyl-5-methoxykynuramine,resveratrol and uric acid[J].Int J Biochem Cell Biol,2001,33(8):775-783.
  • 9中华人民共和国药典委员会 化学.中国药典(第1部)[M].北京:工业出版社,2000.167.
  • 10JangM, CaiL, Udeani G. O. et ah Cancer Chemopreventive Activity of Resveratrol, a Natural Product Derived from Gropes-Science[J]. Science, 1997,275(5 297) :218-220.

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