肺癌同步放化疗配合平消胶囊的免疫状况观察

The observation on the immunity state of lung cancer by radiotherapy in sync with chemotherapy combined with pingxiao capsule

目的:本研究旨在观察肺癌患者同步放化疗中配合平消胶囊的免疫状况,以评价平消胶囊对肺癌患者免疫功能以及生存质量的影响。方法:将60例肺癌病人随机分成两组,单纯放化疗组和放化疗配合平消胶囊组,分别在治疗开始以及治疗完成后3周对患者进行T细胞亚群检测。结果:单纯放化疗组治疗后CD3、CD4、CD4/CD8显著降低(P<0.05),而CD8显著升高(P<0.05);放化疗配合平消胶囊组治疗后CD3、CD4、CD4/CD8升高,尤其对于治疗有效者差异具有显著性。并且放化疗配合平消胶囊组KPS评分较治疗前显著升高。结论:肺癌患者进行同步放化疗治疗后免疫功能下降,而放化疗配合平消胶囊可以提高机体免疫力。

Objective：This research is to observe the immunity state of lung cancer by radiotherapy in sync with chemotherapy combined with pingxiao capsule,and to evaluate the effect on the immune function and the existence qualitative of pingxiao capsule in lung cancer. Method：Sixty lung cancer patients were parted into two groups at random,one is simple radiotherapy in sync with chemotherapy,the other is radiotherapy in sync with chemotherapy combined with pingxiao capsule. All the two groups were carried out T-cell subgroup experiment at the beginning and three weeks after the therapy. Results：After therapy CD3,CD4 and CD4/CD8 all indicates significant lower level （P〈0.05）in the group of simple radiotherapy in sync with chemotherapy. But in the group of radiotherapy in sync with chemotherapy combined with pingxiao capsule CD3,CD4 and CD4/CD8 all indicates higher lever after the therapy,especially to the CR and PR patients（P〈0.05）. And in the second group ,the patients had higher KtXS scores after therapy （P〈0.05）. Conclusion：The immune function indicates lower lever after radiotherapy and chemotherapy in lung cancer,but pingxiao capsule can enhance the immune function of the organism, meanwhile can improve the existence qulatative .