放射性核素全身骨显像对多发性骨髓瘤诊断价值的评价

Diagnostic value of radionuclide whole - body bone imaging for multiple myeloma

目的评价放射性核素全身骨显像诊断多发性骨髓瘤（MM）的价值。方法26例被临床确诊为MM的患者，均进行全身骨显像、X线检查、骨髓穿刺涂片或病理活检及相关实验室检测，综合分析核素骨显像对MM的诊断意义，并通过多次复查骨显像，动态监测MM的治疗效果。结果26例MM患者中，核素骨显像阳性者23例，阳性率88．5％，X线检查阳性者18例，阳性率69．2％。6例患者不同期化疗后，复查全身骨显像显示骨病变范围缩小或病灶数目减少，病灶处放射性有所改变，临床也证实病情改善。结论放射性核素全身骨显像对MM的诊断具有重要价值，并对MM疗效的动态观察具有指导意义，此方法可作为MM诊断和疗效观测的常规手段之一。

Objective To evaluate the diagnostic value of radionuclide whole - body bone imaging for multiple myeloma （MM）. Methods Radionuclide bone imaging, X - ray , marrow puncturing and other related examinations were perfomed in 26 patients with MM. It was totally analyzed that the diagnostic value of radionuclide bone imaging combined with marrow puncturing and other examinations for MM. Some patients were dynamically examined with radionuclide bone imaging in order to estimate the treatment efficacy of MM. Results Among 26 patients, 23 patients had positive radionuclide bone imaging findings, 18 patients had positive X -ray findings, After chemical therapy, radionuclide bone imaging was performed again in 6 of 11 patients, and the image showed that the range or number of abnormal bone focus reduced and the radioactivity of bone focus changed, according with patients ceondition after chemical therapy. Conclusion Radionuclide whole -body bone imaging has important value in diagnosis of MM, It can be available for dynamically monitoring prognosis of treatment of MM. Radionuclide bone imaging can be considered as one of routine examination for diagnosis of MM,