中心性浆液性脉络膜视网膜病变的治疗与远期随访

Treatment and long-term follow-up of central serous chorioretinopathy

目的：评估中药治疗中心性浆液性脉络膜视网膜病变的远期效果。方法：经中药治疗的87例（93只眼）中心性浆液性视网膜病变患者的临床随访资料进行了回顾性研究。对其中记录完整的54例（58只眼）进行了随访，随访检查项目包括视力、裂隙灯显微镜、眼底、眼底照像和眼底荧光血管造影等。结果：进入随访研究的54例患者中23例得到随访资料，随访率42.59％。随访时间2年1月至10年4个月。23例随访患者中复发7例，复发率30．44％。复发和未复发病例病变部位的视网膜色素上皮损害在随访期间均发生了不同程度的萎缩。结论：在平均7年6个月的随访期间治愈患者中有一定的复发率；复发和未复发病例的视网膜色素上皮荧光素渗漏消失后，其色素上皮的损害在随访期间发生了不同程度的变化。

To asses the long-term outcome of central serous chorioretinopathy(CSR) among a group of patoemts previously treated with traditional Chinese medicine.METHODS: A retrospective study was Performed on the treatment of CSR with traditionalChinese medicine according to the clinical data of 87 patients (93 eyes). Fifty-four patients(58eyes ) in the group, whose records of history were complete, were examined in the follow-upstudy, including history taking, as well as visual acuity, ophthalmoscopy, biomicroscopy, fundusphotography, and fluorescin angiography. RESULTS: Twenty-three cases of 54 patients understudy were available for follow-up from 2 years and one month to 10 years and four months, thefollow-up rate was 42.59%. There were 7 clinically documented recurrence among the 23 eyes, therate of recurrence was 30.44%. The retinal pigment epithelium atrophy was found in the site offluorescin dye leakage for both the cases with and without recurrence, and the extent of atrophywas various. CONCLUSIONS: For the recovery patients still exists certain probability of recur-rence(30.44%) during a follow-up average of 7 years and 6 months. After disapPearance offluorescin leakage in pigment epithelium with or without recurrence, the damage of pigmentepithelium still changed in some extent during the follow-up.