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异位F1F0 ATP合酶及其与肿瘤血管生成的关系 被引量:2

Ectopic F1F0 ATP Synthase and Tumor Angiogenesis
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摘要 异位F1F0 ATP合酶作为一个细胞表面受体,它可表达在血管内皮细胞表面黏合血管抑素(angiostatin,又称血管生成抑制素),调节细胞表面ATP水平,进而影响血管内皮细胞的增殖和分化。血管抑素在低pH值时可以黏合并阻滞细胞表面的F1F0ATP合酶,继而干扰其活动;籍此发挥强大的内皮细胞杀伤效应,在抑制肿瘤血管生成中起着重要作用。
出处 《中国肿瘤》 CAS 2007年第8期610-612,共3页 China Cancer
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