摘要
检测21例支气管哮喘患儿血清12种微量元素、钙镁含量,以及外周血T细胞亚群等变化。结果:哮喘组血清锌、铁、铜、锂、钙均值明显低于对照组,血清铬均值高于对照组;CD+3、CD+8细胞百分率及T细胞增殖反应较对照组显著降低,CD+4/CD+8比值则显著增高。提示哮喘患儿存在多种微量元素水平降低或缺乏,与T细胞亚群及功能失调有一定关系。
Concentration of 12 kinds of trace elements and Ca,Mg in serum and T lymphocyte subsets in peripheral blood were measured in 21 children with bronchial asthma.Compared with controls,the means of Zu,Fe,Cu,Li,Ca were decreased and Cr was increased significantly,the percentages of CD + 3,CD + 8cell and T lymphocyte proliferative function were also lowered,but the rate of CD + 4/CD + 8cell was raised in asthma group.The results suggest that patients with asthma exist deficiency or insufficiency of many kinds of trace elements in serum,and the trace elements deficiency or insufficiency is related to the irregulation of T lymphocyte subsets.
出处
《滨州医学院学报》
1997年第1期14-16,共3页
Journal of Binzhou Medical University
基金
山东省卫生厅科研基金
关键词
哮喘
微量元素
T细胞亚群
儿童
bronchial asthma
trace element
T lymphocyte subsets
children