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在梗阻性肥厚型心肌病经酒精间隔消融后有或无右束支传导阻滞的患者中采用心脏磁共振成像评估心肌梗死和逆转重构的程度

Extent of Myocardial Infarction and Reverse Remodeling Assessed by Cardiac Magnetic Resonance in Patients With and Without Right Bundle Branch Block Following Alcohol Septal Ablation for Obstructive Hypertrophic Cardiomyopathy
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摘要 经皮酒精间隔消融(ASA)是一种用于缓解梗阻性肥厚型心肌病患者难治性症状的已确立技术。多数患者在行ASA后出现右束支传导阻滞(RBBB),但是尚不清楚出现RBBB的患者是否具有与无RBBB患者类似的梗死特征,梗死特征可能会影响左心室(LV)压力阶差降低和逆转重构。纳入连续27例患者(15例男性,12例女性,年龄62±16岁),分别在基线时和ASA后1个月、6个月(n=25)时进行心电图和心脏磁共振成像检查。1个月时根据延迟对比增强心脏磁共振成像确定梗死区大小和位置。与无RBBB的患者相比,17例出现RBBB的患者有梗死面积较大的倾向(CK-MB251±92U vs 148±97U,P=0.03; Percutaneous alcohol septal ablation(ASA) is an established technique for the relief of refractory symptoms in patients with obstructive hypertrophic cardiomyopathy. Most subjects develop right bundle branch block(RBBB) after ASA, but it is not known whether these patients have similar infarct characteristics, which may influence left ventricular(LV) pressure gradient reduction and reverse remodeling, compared with those without RBBB. Twen- ty-seven consecutive patients(15 men, 12 women; mean age 62 + 16 years) were studied with electrocardiography and cardiac magnetic resonance imaging at baseline and 1 and 6 months(n = 25) after ASA.
机构地区 Cardiology Department
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