摘要
背景：利用经胸多普勒超声心动图行冠状动脉血流储备（CFR）评估已被用于临床，CFR降低被认为是高血压终末器官受损的灵敏指标；然而，迄今该方法尚未被用于评估高血压前期受试者的CFR。因此，本研究旨在评估高血压前期受试者的CFR。方法和结果：通过经胸多普勒超声心动图检测40例高血压前期受试者、60例高血压患者和50例血压正常健康志愿者的CFR。所有受试者均无系统性疾病。3组受试者之间年龄、性别、体重指数、心率、血脂、空腹血糖和血红蛋白水平均相似。
BACKGROUND - The assessment of coronary flow reserve （CFR） by transthoracic Doppler echocardiography has recently been introduced into CFR has been suggested to clinical practice, and reduced be a sensitive indicator of hypertensive endorgan damage; however, to date, this methodology has not been used t0 evaluate CFR in subjects with prehypertension. Accordingly, the present study was designed to evaluate CFR in subjects with prehypertension. METHODS AND RESULTS - We measured CFR of 40 subjects with prehypertension, 60 patients with hyperten- sion, and 50 normotensive healthy volunteers using transthoracic Doppler echocardiography. None of the sub- jects had any systemic disease. Age, gender, body mass index, heart rate, lipid profiles, fasting glucose levels, and hemoglobin were similar among the 3 groups.
