摘要
背景：经皮冠状动脉介入（PCI）时，冠状动脉内多普勒导丝可实时检测并定量微栓塞。本研究旨在探讨行择期PCI时，多普勒检出微栓塞的频率是否与肌坏死发生率相关。方法和结果：研究对象为52例连续的冠状动脉疾病患者（年龄64土10岁，男性36例，女性16例），这些患者均因单支血管狭窄行择期PCI。利用冠状动脉内多普勒超声比较了22例围手术期非ST段抬高型心肌梗死（pNSTEMI）患者和30例无pNSTEMI患者在PCI过程中微栓塞的检出率。这两组患者在临床和操作特征方面均具有可比性。
BACKGROUND - Intracoronary used for real-time detection and Doppler guidewires can be quantification of microembolism during percutaneous coronary interventions （PCIs） . We investigated whether the frequency of Doppler-detected microembolism is related to the incidence of myonecrosis during elective PCI. METHODS AND RESULTS - The study population included 52 consecutive patients（aged 64 ±10 years; 36 men, 16 women） with coronary artery disease who underwent elective PCI of a single-vessel stenosis. Using intracoronary Doppler ultrasound, we compared the frequency of microembolism during PCI in 22 patients with periprocedural non-ST-segment elevation myocardial infarctions（pNSTEMI） and 30 patients without pNSTEMI.
