翼状胬肉两种手术方法的临床效果比较

Comparison of the therapeutic effect of two different surgical procedures for pterygium

目的对比两种手术方法治疗翼状胬肉的临床效果。方法翼状胬肉46例(51只眼)随机分成两组,每组均为23例。第1组,翼状胬肉切除加自体角膜缘干细胞移植;第2组,翼状胬肉切除加带蒂结膜瓣转移术中联合应用丝裂霉素C。观察术后角膜上皮修复、角膜缘新生血管及翼状胬肉复发情况。结果术后随诊6～36月,第1组中有1只眼复发(4.35%),第2组有2只眼复发(8.70%)。结论翼状胬肉切除加自体角膜缘干细胞移植及翼状胬肉切除加带蒂结膜瓣转移术中联合应用丝裂霉素C均能有效阻止胬肉复发。但前者在手术安全性、舒适性、术后并发症等方面更具优势。

Objective To evaluate the therapeutic effect of two different surgical procedures for pterygium. Methods A total of 46 patients （ 51 eyes ） were randomly divided into two groups ： group A （ 23cases ） underwent excision of pterygium with limbal epithelial autograft and group B underwent excision of pterygium with transferation of pedide conjunctival flap and application of mitomycin-C in operation. The recurrence rate,eplthelial recovering of corneal wound and neovascularization of corneal limbus were observed respectively. Results All cases were followed up for 6 ～ 36 months. 1 eye in group A was recurred （4.35% ） as 2 eyes in group B pterygium recurrence observed （8.7%）. Conclusion Both limbal epithelial autograft and transferafion of pedicle conjunctival flap with application of mitomycin-C in operation are effective in treating of pterygium. But the former appears to be more safe,comfortable and less complications than the latter.