危重儿代谢性碱中毒82例临床分析

Clinical Analysis of Metabolic Alkalosis in 82 Cases of Critically Acute Children

目的 探讨引起危重儿代谢性碱中毒（代碱）的原因和临床特点.方法 检测危重儿血气分析390例,并分析代碱的类型及代碱严重程度与死亡率的关系.结果 共检测出代碱82例（21%）,其中代碱＋呼酸26例,代碱＋呼碱24例,代碱＋代酸5例,单纯代碱27例.pH7.45～7.60 21例,死亡率4.8%,pH7.60～7.70 39例,死亡率10.26%,pH7.70～7.90 22例,死亡率22.7%,各组间差异显著（P＜0.01）.结论 危重儿代碱随着pH增高,死亡率明显增高,故临床应注意避免其发生并及时纠正,以提高危重儿抢救成功率.

Objective To explore the causes and clinical features of metabolic alkalosis in critically acute children. Methods Blood-gas analysis were detected in 390 cases of critically acute children. The relationship of the types and severity of metabolic alkalosis and the mortality rate was analysed. Results 82（12% ） cases of metabolic alkalosis were detected. Of all there were 26 cases of metabolic alkalosis with respiratory acidosis,24 cases of metabolic alkalosis with respiratory alkalosis,5 cases of metabalhc alkalosis with metabolic acidosis,5 cases of simple metabolic alkalosis. When the range of pH was 7.45 ～ 7.60（21 cases） .7.60 ～ 7.70 （39 cases） or 7.70 ～ 7.90 （22 cases） , the mortality was respectively 4.8% .10.26% or 22.7%. There were significantly differences among each groups. Condusion With the elevation of pH value, the mortality rate of critically acute children rises significantly. Therefore, to raise the successful rescue rate of critically acute children,the metabolic alkolosis should be avoided and corrected in time.